Bruno Weber Lab Team Publications News Contact

Pioneering the futureof brain science

Newest publication

Long-Term Treatment With Interleukin-6 Receptor Inhibitor Tocilizumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

About

Pioneering the future of brain science through advanced imaging and metabolic research. We decode neural energetics and glial function to revolutionize our understanding of the living brain.

Latest publications

View all 121
Beilmann V, +16 more

Astroglial Disinhibition of Cortical Circuits Disrupts Cognition via Kynurenic Acid in Mice

Nature Communications
2026
Condrau J, +18 more

Intrinsic Endothelial Remodeling Drives Brain Capillary Repair

Neuron
2026
Beilmann V, +13 more

ECgo: All-Optical Induction of Single Endothelial Cell Injury and Capillary Occlusion in the Brain

Proceedings of the National Academy of Sciences of the United States of America
2026

What we’re working on

Glial Biology

Astrocytes have emerged as major players in intercellular signaling, which contribute to brain information processing, synaptic plasticity and neurovascular coupling. Astrocyte intracellular calcium signals are central to this communication and are triggered by neurotransmitter receptors in response to synaptic input.

Brain Energy Metabolism

For decades the notion that glucose is taken up and metabolized by individual brain cells according to their relative need was carved in stone. Things are much more complex. We now know that the metabolic support of the brain is a concerted effort between the vascular system, glial cells, and neurons.

Cerebrovascular Biology

Our lab has spearheaded the use of reconstructions of realistic cortical vascular networks to investigate the neurovascular unit. We published work on the vascular topology, oxygen transport and fluid dynamics at the single erythrocyte level. This work has been carried out in a long-standing collaboration with colleagues at the Institute for Fluid Dynamics at the ETH Zurich.

Brain Energy Metabolism

For decades the notion that glucose is taken up and metabolized by individual brain cells according to their relative need was carved in stone. Things are much more complex. We now know that the metabolic support of the brain is a concerted effort between the vascular system, glial cells, and neurons.

Latest news

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PD Dr. Marina Herwerth

Swiss Multiple Sclerosis Society Grants Funding to Marina Herwerth’s Research Project

15 August 2025
Prof. Dr. Bruno Weber

Bruno Weber holds opening plenary lecture at the 2025 Glia Meeting in Marseille

3 August 2025
Viktor Beilmann, +1 more

Jeanne Droux and Viktor Beilmann Awarded Prestigious UZH Candoc Grant

12 June 2025
Universität Zürich

Institute of Pharmacology and Toxicology

We are working on breakthroughs in our current understanding of normal brain function and how we can target diseases of the central nervous system with novel approaches. We teach modern pharmacology to medical and science students.

About us

Experts

Our team studies brain energy metabolism and glial biology with the tools of tomorrow. Join us on this exciting journey.

Meet the Team 25